- विज्ञापन -
New Delhi: Pediatric cancer is a heart-wrenching diagnosis that no parent ever wants to hear. While most cancers in children are not directly inherited, recent research has shed light on how genetics can play a role in the development of cancer in young patients. Understanding the genetic factors behind pediatric cancer can help parents make informed decisions and advocate for the best possible care for their child. Read on as we will explore the role of genetics in pediatric cancer, how genetic mutations contribute to cancer development and what every parent should know.
♦What is pediatric cancer?
Pediatric cancer refers to cancers that occur in children and adolescents, typically under the age of 18. While cancer is more common in adults, pediatric cancers, even though rare, can be equally devastating.
Common types of pediatric cancer include leukemia, lymphoma, brain tumours, neuroblastoma, Wilms tumor, and bone tumors. Unlike adult cancers, which are often linked to environmental factors or lifestyle choices, pediatric cancers tend to have different causes and may sometimes involve genetic factors.
Genetics plays a significant role in the development of cancer. In children, certain genetic mutations or inherited conditions can increase the risk of developing cancer. In most cases, these cancers are not passed down directly from parent to child but rather arise from spontaneous genetic mutations. However, some children inherit genetic mutations that predispose them to certain types of cancer.
♦The role of genetic testing
Genetic testing can play a crucial role in identifying children at higher risk for cancer. Through a blood test, doctors can screen for inherited genetic mutations and provide insight into the risk of developing certain cancers. If a child has a family history of cancer or presents with symptoms of a genetic syndrome, genetic testing may help guide medical decisions.
♦The role of genomics in pediatric cancer
Genomics has revolutionised the understanding of pediatric cancer by studying both the child’s and tumour’s genetic makeup. Tumour profiling helps provide a precise diagnosis and tailor treatments to target specific genetic mutations, improving treatment efficacy and reducing unnecessary interventions. Additionally, genomic testing aids in early detection by identifying children at higher cancer risk, enabling closer monitoring and earlier interventions for better outcomes.
♦What every parent should know
As a parent, it is important to understand that the majority of childhood cancers are not directly inherited. However, some genetic conditions do increase a child’s risk, and early detection through genetic testing can help identify potential risks.
Not all pediatric cancers are genetic: Most childhood cancers occur due to spontaneous mutations, not inherited conditions. However, inherited genetic mutations can increase the risk for certain types of cancer.
♦Genetic testing can provide valuable information:
If your child has a family history of cancer or exhibits signs of a genetic syndrome, genetic testing may help identify potential risks and guide treatment.
Genetic counseling is important: If your child is diagnosed with cancer or if there’s a family history of cancer, genetic counseling can provide support and guidance. A genetic counselor can help you understand the results of genetic tests and help make informed decisions about your child’s care.
♦Early intervention improves outcomes:
Inherited genetic syndromes can sometimes be detected early, leading to closer monitoring and earlier interventions, which can improve the chances of successful treatment. Early detection through genetic testing offers opportunities for more precise and effective treatment plans, which could significantly impact a child’s chances of recovery.
“For parents, staying proactive and seeking genetic counseling when appropriate can make a real difference in navigating the complexities of pediatric cancer. By equipping themselves with the right knowledge, parents can ensure that they are making the most informed decisions for their child’s health and future. The majority of childhood cancers are curable, especially if detected early and managed in an appropriate manner.
